Correlation between those initial activated partial thromboplastin time
(aPTT) results that were in the detectable range (n = 53; 78%) and their final, reduced values.
Relationship between diluted prothrombin time (dPT) ratios and prolongation of activated partial thromboplastin time
(aPTT) in the presence of lepirudin.
2] Nonstandard abbreviations: DTI, direct thrombin inhibitor; DFXaI, direct factor Xa inhibitor; PT, prothrombin time; APTT, activated partial thromboplastin time
Parameters were retrieved electronically and by manual chart review, including the exact timing of changes in the bivalirudin infusion and the corresponding partial thromboplastin time
(PTT) values that were obtained for clinical monitoring at that time.
1) The most common way to monitor argatroban is using the activated partial thromboplastin time
(aPTT) test, which is also recommended by the manufacturer for patients receiving prophylaxis or treatment for HIT.
Prior to undergoing a renal biopsy, a prothrombin time (PT) and activated partial thromboplastin time
(aPTT) were ordered and the patient was noted to have an elevated PT of 22.
It is advisable to discontinue warfarin near term and switch to intravenous heparin to an activated partial thromboplastin time
This form of heparin has a half-life of 90 to 120 minutes, and its activity may be monitored by measuring the activated partial thromboplastin time
5 s (RI, 9-13 s); activated partial thromboplastin time
1,2) The activated partial thromboplastin time
(aPTT) is the most common monitoring method; however, it is only a surrogate measure of the plasma heparin concentration.
The other data collected included demographic factors, diagnosis, Acute Physiology and Chronic Health Evaluation II score, Sequential Organ Failure Assessment score on the day of TEG testing (9), C-reactive protein concentration (10), fibrinogen concentration, International Normalised Ratio, activated partial thromboplastin time
, active infection requiring antibiotics, thrombotic complications (deep vein thrombosis, pulmonary embolism, thrombotic stroke) and hospital mortality.
In patients with severe disease, hemoglobin concentrations and platelet counts were significantly lower, and leukocyte counts, prothrombin time, and partial thromboplastin time
were elevated, compared with results for patients with uncomplicated malaria (Table 2).