Pathogenicity


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pathogenicity

[‚path·ə·jə′nis·əd·ē]
(medicine)
The ability of an organism to enter a host and cause disease.

Pathogenicity

 

the ability of a microorganism to cause infectious disease. Pathogenicity varies with the virulence of the infectious agent and with the susceptibility of the infected organisms. Thus for every microbe, it is a relative characteristic that depends on the species, age, sex, and physiological condition of the infected organism.

Pathogenicity develops as a result of a microbial species’ long evolutionary adaptation to the presence of a particular host species. Individual strains from a single microbial species differ in pathogenicity.

References in periodicals archive ?
The pathogenicity of the H5N8 virus was evaluated in mallards, Baikal teals, and domestic ducks.
Structural and sequence diversity of the pathogenicity island of uropathogenic Escherichia coli which encodes the USP protein.
The pathogenicity island studied is a prototype of a new family of virulent DNA recently discovered which also can be transferred to other species of bacteria such as Listeria monocytogenes, responsible for a large number of intoxications.
Past work has already identified primate genes that hinder infection, and the new work could help clarify what causes differences in pathogenicity among species and individuals.
23) A series of elegant experiments, from Jim Kaper's group, showed that the factors required for attaching-effacing capacity are encoded by genes co-located within a pathogenicity island, known as the locus for enterocyte effacement (LEE), which is completely absent from E.
However, after the initial isolation, GenBank played the crucial role of helping to determine whether this was a new disease or an old virus that had evolved a new pathogenicity.
This effort has led to the publication of booklets dealing with methods, survival and growth, pathogenicity and virulence, control and epidemiology of VTEC, available at http://www.
hominis strains, which may relate to the conflicting data on the pathogenicity of the organism.
So far, no conclusions can be drawn about the potential pathogenicity of PERVs if cross-species infection occurs," wrote Jonathan Stoye, MD, of the National Institute for Medical Research in London, in a commentary accompanying the three articles.
DNA base modifications such as methylation have an important role in a wide variety of biological processes such as growth and aging, immunity, bacterial pathogenicity, and disease development.