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Pentylenetetrazol

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
pentylenetetrazol [¦pent·əl‚ēn′te·trə‚zȯl]
(pharmacology)
C6H10N4A central nervous system stimulant used as an analeptic.
Pentylenetetrazol 

or leptazol, a medicinal preparation that exerts a stimulating effect on the central nervous system and stimulates respiration and blood circulation; in large doses it induces convulsions. It is taken internally (in tablets) or injected intramuscularly, subcutaneously, or intravenously (in solution) to stimulate cardiovascular activity and respiration and as a means of terminating or attenuating narcosis; it is sometimes used in convulsive therapy for schizophrenia.
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Industrias Quimicas), valproic acid (Abbot Laboratorios do Brasil), baclofen (Biogalenica Quimica e Farmaceutica Ltda--CibaGeigy), diazepam (Roche Produtos Quimicos e Farmaceuticos), phenobarbital (Rhodia Produtos Quimicos e Farmaceuticos), pentylenetetrazol (Sigma Chemical Co.
Nantenine alkaloid presents anticonvulsant effect on two classical ... by Riberio, R.A.; Leite, J.R. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
In the pentylenetetrazol (PTZ) test performed in rats, EHT 0202 increased the doses of PTZ required to induce clonic and tonic convulsions, as well as death.
EXONHIT Expands Neurological Research Activities to Epilepsy by Business Wire
 
 
 
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