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clinical trial
(redirected from Phase I trials)

   Also found in: Medical, Wikipedia, Hutchinson 0.02 sec.
clinical trial [¦klin·i·kəl ′trīl]
(medicine)
A research study used to find better ways to treat individuals with a specific disease, patients are evaluated after being administered a new treatment or drug.


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The "inpatient" portion of Phase I trials usually lasts from a day or two to a week (though follow up can last up to about a month), and are designed to assess the safety of a compound and study its pharmacokinetics (Pk--what the body does to the drug) and pharmacodynamics (Pd--what the drug does to the body).
This trial also used a slightly different dosing schedule, although dosages found safe in the company's phase I trials actually exceeded dosages given in the phase II trial.
We are excited about the prospects of Kemia's first new medicine, which was designed and synthesized in Kemia's drug discovery group and then brought through Phase I trials by Kemia's development team.
 
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