Two new phleboviruses
recently detected in Ixodes ticks in the northeastern United States are genetically unrelated to HRTV but raise the possibility that additional undiscovered phleboviruses
Detection and identification of Toscana and other phleboviruses
by RT-nested-PCR assays with degenerated primers.
(family Bunyaviridae) are endemic in Mediterranean countries, and at least 3 serotypes are associated with disease in humans: TOSV, SFNV, and SFSV.
Genetic characterization showed that the virus is closely related to 2 newly discovered tick-borne zoonotic phleboviruses
(SFTSV and HRTV) that were responsible for severe disease and death in humans in 4 separate countries in Asia and North America.
The conclusion was based on our knowledge, at the time our manuscript was submitted, that in North America no other known phleboviruses
of this expanded Uukuniemi group that contains SFTSV and HLV were reported to be cross-reactive with SFTSV.
We found that 2 phleboviruses
belonging to the Sandfly fever Naples virus species, TOSV and Punique virus, are cocirculating in northern Tunisia.
The following viruses were considered: human enterovirus (HEV), herpesviruses, Toscana virus (TOSV), mumps virus, phleboviruses
, flaviviruses, arenaviruses, and adenoviruses.
To the Editor: Phleboviruses
(family Bunyaviridae, genus Phlebovirus) are arthropod-borne, single-stranded, RNA viruses.
The elevated IgM titer in the population in Corsica could indicate 1) recent virus contacts; 2) recent infections with a new TOSV strain circulating in Corsica; or 3) presence of related phleboviruses
that are inducing cross-reactivity in the N protein-based IgM ELISA.
No similar rise in neutralizing antibodies to serologically related phleboviruses
Rapid detection of important human pathogenic phleboviruses
According to the Eighth Report of the International Committee on Taxonomy of Viruses, phleboviruses
are classified into 9 serocomplexes (1), 1 of which includes Rift Valley fever virus (RVFV), a deadly pathogen for cattle and humans.