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(organic chemistry)
C6H3(OH)3·2H2O White to yellow crystals with a melting point of 212-217°C when heated rapidly and 200-209°C when heated slowly; soluble in alcohol and ether; used as a bone decalcifying agent, as a floral preservative, and in the manufacture of pharmaceuticals.



(also 1,3,5-trihydroxy-benzene), one of the trihydric phenols. The structural formula is

Phloroglucinol occurs as colorless crystals with a sweet taste that are readily soluble in alcohol and ether. The melting point is 217°–219°C. The compound forms a dihydrate with a melting point of 117°C.

Phloroglucinol is prepared mainly through the hydrolysis of the hydrochloride of 1,3,5-triaminobenzene. In glycoside form, phloroglucinol is a constituent of many natural substances (flavones, catechin). The compound is used in analytical chemistry, for example, in quantitative and qualitative determinations of pentoses and pentosans. (Hydrolysis of pentosans in the presence of hydrochloric acid yields furfural, which combines with phloroglucinol to form a red solid that is insoluble in water.)

References in periodicals archive ?
Iodine Resublimed AR Phloroglucinol (1,3,5-trihydroxybenzene), 2,7, Dichlorofluorescein AR, Pyridine AR Grade Emp.
The metabolites investigated were dimeric phloroglucinol derivatives, benzophenones and benzopyrans.
Traveler's gastroenteritis was diagnosed, and symptomatic treatment with acetaminophen, phloroglucinol glucoside, and acetorphan was prescribed.
Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi.
Briefly, 50 [micro]L of the collected plasma was added to 5 mL of phloroglucinol (Sigma Chemical Inc.
A phloroglucinol derivative from the brown alga Eisenia bicyclis has been found to be effective in inhibiting glycation and alpha-amylase (Okada et al.
To test for the presence of lignin in the thickenings, transverse and longitudinal sections were stained with phloroglucinol (1%) with HC1 (25%) (D'Ambrogio de Argiieso, 1986).
Phloroglucinol (PG) is a phenolic compound predominantly found in xylem sap of apple and is known to promote growth and development in a number of plant species such as Chinchona ledgeriana, apple cultivars and cocoa [13].
perforatum include hypericins; procyanidins; phloroglucinol derivatives including hyperforin, flavonoids and xanthones (Nahrstedt 1997).
Randomized trial of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi.
pyrogallol, catechol, phloroglucinol and femlic acid, are reported to act synergistically with auxin on AR (James & Thurbon, 1981).