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phosphate
(redirected from Phosphate binders)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
phosphate, salt or ester of phosphoric acid phosphoric acid, any one of three chemical compounds made up of phosphorus , oxygen, and hydrogen (see acids and bases ). The most common, orthophosphoric acid, H3PO4, is usually simply called phosphoric acid.
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, H3PO4. Because phosphoric acid is tribasic (having three replaceable hydrogen atoms), it forms monophosphate, diphosphate, and triphosphate salts in which one, two, or three of the hydrogens of the acid are replaced, respectively. Because replaceable hydrogens remain in monophosphates and diphosphates, they are sometimes called acid phosphates. The most important inorganic phosphate is calcium phosphate, Ca3(PO4)2. It makes up the larger part of phosphate rock, a mineral that is abundantly distributed throughout the world. Since calcium phosphate is only slightly soluble in water, it is not very suitable as a source of the phosphorus necessary for plant life; however, by treating it with sulfuric acid the soluble calcium acid phosphate known as superphosphate superphosphate or superphosphate of lime, Ca(H2PO4)2, is a compound produced by treating rock phosphate with sulfuric acid or phosphoric acid, or a mixture of the two.
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 of lime is formed. Other important inorganic phosphates include ammonium phosphate, important as a fertilizer; trisodium phosphate, used in detergents and for softening water; and disodium phosphate, used to some extent in medicine and in preparing baking powders. Various acid phosphates, e.g., those of calcium, magnesium, and sodium, are sometimes present in carbonated beverages. Microcosmic salt, used in certain bead tests in chemical analysis, is sodium ammonium phosphate. Organic phosphates play an important role in metabolism. For example, in the metabolism of sugars (which have hydroxyl groups, -OH, in their molecules), phosphate esters are often formed as an intermediate compound. Formation of these esters is called phosphorylation. Nucleotides are phosphate esters that play an important role in the conservation and use of the energy released in the metabolism of foods in the body; adenosine triphosphate adenosine triphosphate (ATP) (ədĕn`əsēn trī'fŏs`fāt)
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 is an important nucleotide. DNA and RNA (see nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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) are complex polymeric organic phosphates.

phosphate

Any of numerous chemical compounds related to phosphoric acid (H3PO4). Phosphate salts are inorganic compounds containing the phosphate ion (PO43−), the hydrogen phosphate ion (HPO42−), or the dihydrogen phosphate ion (H2PO4), along with any cation. Phosphate esters are organic compounds in which the hydrogens of phosphoric acid are replaced by organic groups (e.g., methyl, ethyl, phenyl), with one of their carbon atoms bonding to an oxygen atom in the phosphate group. Nucleic acids and ATP both contain phosphate; bones and teeth contain calcium phosphate. Phosphate rock (mainly calcium phosphate) is one of the four most important basic chemical commodities. Phosphates were formerly used in detergents, which washed into rivers and lakes, causing water blooms of algae and bacteria (see eutrophication); such use is now generally outlawed or regulated. Phosphates are still used in fertilizers, baking powder, and toothpaste.


phosphate
any salt or ester of any phosphoric acid, esp a salt of orthophosphoric acid

phosphate [′fä‚sfāt]
(chemistry)
Generic term for any compound containing a phosphate group (PO43-), such as potassium phosphate, K3PO4.
Generic term for a phosphate-containing fertilizer material.
(mineralogy)
A mineral compound characterized by a tetrahedral ionic group of phosphate and oxygen, PO43-.


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ESRD patients with hyperphosphataemia are prescribed phosphate binders to reduce the amount of phosphorus absorbed by the body.
Ester-cured phenolics, urea-free furans, silicates and inorganic phosphate binders contain little or no nitrogen.
High phosphate levels can be avoided with phosphate binders and dietary restriction of phosphate.
 
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