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Piperazine

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piperazine [pī′par·ə‚zēn]
(organic chemistry)
C4H10N2A cyclic compound; colorless, deliquescent crystals, melting at 104-107°C; soluble in water, alcohol, glycerol, and glycols; absorbs carbon dioxide from air; used in medicine.

Piperazine 

(or diethylenediimine), a heterocyclic compound; colorless crystals. Melting point, 104°C; boiling point, 145°-146°C. Poorly soluble in water and ether; readily soluble in alcohol.

Piperazine is a strong base. It is obtained by hydrogenation of pyrazine or 2,5-piperazinedione or condensation of dibromo-ethane with ammonia. Piperazine and its derivatives are used in analytical chemistry for microcrystalloscopic identification of Mo, V, and W and in medicine (in the form of salts of adipinic, citric, phosphoric, or sulfuric acid) as an anthelmintic in cases of ascariasis and enterobiasis.



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Officers found and confiscated from the man 250 piperazine pills, worth around 1,000 lats on the black market.
N'-dimethylpiperazine (DMP) (from Acros), N',N-dimethylformamide (DMF), hexahydropyridine and piperazine (from Chinese Medicine Group), A-BPE-10 and TMPTA (from Shin-nakamura Chemical Co.
This bicyclic intermediate dimerized to form a five-ring compound with a central piperazine ring, which was characterized by electrospray ionization-liquid chromatography/mass spectrometry, NMR, and x-ray crystallography.
 
 
 
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