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Plasma Cell
(redirected from Plasma cells)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
plasma cell [′plazĀ·mə ‚sel]
(histology)

Plasma Cell 

a type of cell of the connective and hematopoietic tissues. Plasma cells are formed in vertebrates and man from hematopoietic stem cells of the bone marrow. Their principal function is the production of antibodies. Plasma cells are found in lymphatic and hematopoietic tissues, in serous membranes, and in the connective tissues of the organs of digestion and respiration; they accumulate during immunological reactions, for example, to foreign tissues and infection. They are round and have an eccentric nucleus that contains dense clumps of chromatin. The cytoplasm contains large amounts of ribonucleic acid and therefore stains strongly with basic stains. The only region of a plasma cell that absorbs little stain is near the nucleus, where the Golgi complex and the centrosome are located. The plasma cell also exhibits a well-developed endoplasmic reticulum and an abundance of ribosomes, which are characteristic of cells that actively synthesize and secrete proteins.

N. G. KHRUSHCHOV



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Myeloma UK has launched the Myeloma Clinical Trial Network, which will run trials of new drugs for myeloma, a cancer of the plasma cells, which is diagnosed in nearly 4,000 people in the UK each year.
It's a cancer of white blood cells, or plasma cells, that produce antibodies.
Because plasma cells produce a larger quantity of light chains than heavy chains, the excess light chains enter the bloodstream as "free" light chains (FLC).
 
 
 
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