Plasmalogen

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plasmalogen

[plaz′mal·ə·jən]
(biochemistry)
Any of a group of glycerol-based phospholipids in which a fatty acid group is replaced by a fatty aldehyde.

Plasmalogen

 

any of a group of naturally occurring lipids belonging to phosphoglycerides, or phosphatides. Plasmalogens were first discovered in 1924 in blood plasma. They are widely distributed in animal tissues, for example, the brain, heart, and skeletal muscles, as well as in plant tissues, for example, algae and the fruits of leguminous plants.

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1988) A possible role for plasmalogens in protecting animal cells against photosensitized killing.
1986) Isolation of animal cell mutants deficient in plasmalogen biosynthesis and peroxisome assembly.
RCDP type 2 and 3 are single enzyme deficiencies in the plasmalogen biosynthesis pathway.
Biochemical investigations like RBC plasmalogen levels and phytanic acid levels could not be done because of financial constraints.
2] Rhizomelic chondrodysplasia punctata is a disorder caused by abnormal peroxisomal function which can be mediated both through disorders of biosynthesis, for example, peroxisomal assembly (RDCP1) and by single enzyme defects affecting plasmalogen synthesis (RCDP2, RCDP3).
Functions and biosynthesis of plasmalogens in health and disease.
Fatty acids of serine, ethanolamine, and choline plasmalogens in some marine bivalves.
The biological significance of plasmalogens in defense against oxidative damage.
Plasmalogens and O-alkylglycerophospholipids in aquatic animals.
Relative high percentages of the plasmalogen derivatives 16:0DMA and 18:0DMA were also detected.
However, these authors found an increase in PC from 29% to 43% on the expense of plasmalogens during conditioning of P.