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(organic chemistry)
A natural or synthetic electrolyte with high molecular weight, such as proteins, polysaccharides, and alkyl addition products of polyvinyl pyridine; can be a weak or strong electrolyte; when dissociated in solution, it does not give uniform distribution of positive and negative ions (the ions of one sign are bound to the polymer chain while the ions of the other sign diffuse through the solution).



a polymer electrolyte, that is, a polymer that dissociates into ions in solution. A large number of periodically repeating charges arises in each macromolecule during dissociation. Polyelectrolytes are divided into polyacids (for example, polyacrylic acids), polybases (such as polyvinyl pyridinium), and polyampholytes (copolymers containing both basic and acidic groups). Most polyelectrolytes contain weak acidic or basic groups and therefore are ionized only in the presence of a strong base (for a polyacid) or strong acid (for a polybase).

Primary biopolymers such as proteins and nucleic acids are among the polyelectrolytes. Cross-linked polyelectrolytes, which are prepared by the introduction of readily dissociating groups (for example, sulfo and amino groups) into various cross-linked polymers, are of great importance to industry and laboratory practice. The most valuable cross-linked polyelectrolytes are ion-exchange resins.

The dissociating groups in the polymer molecules determine the solubility of polyelectrolytes in water and other polar liquids. For example, a sulfonated linear polystyrene dissolves freely in water, although polystyrene itself is one of the most water-resistant polymers known. Cross-linked polyelectrolytes of three-dimensional structure swell in water rather than dissolving. The properties of polyelectrolyte molecules in solution are determined by the electrostatic interaction of charged groups in the chain with one another and with low-molecular-weight ions in the solution. The strong electrostatic field generated by the charges in the polyelectrolyte molecule holds a large number of oppositely charged ions close to the molecule. The electrostatic repulsion of groups of like charge leads to a substantial alteration of the macromolecular conformations in solutions: the effective size of the molecules increases, and the coiled chains straighten out, assuming an approximately linear form as the degree of polyelectrolyte dissociation increases. The physicochemical properties of solutions also undergo considerable alteration (for example, solution viscosity increases by hundreds and thousands; the higher the concentration, the greater the viscosity). The theory that was developed for solutions of low-molecular-weight electrolytes ceases to be valid for polyelectrolyte solutions. The low-molecular-weight ions that appear during the dissociation of polar groups of these polyelectrolytes create a diffuse shell around the oppositely charged surface of the polymer and may to some degree be replaced by other ions of like sign.


Tager, A. A. Fiziko-khimiia polimerov, 2nd ed. Moscow, 1968.
Rice, S. A., and M. Nagasawa. Polyelectrolyte Solutions: A Theoretical Introduction. London-New York, 1961.


References in periodicals archive ?
9,14,15 This is believed to occur because of electrostatic interactions between the polycation and the ON, resulting in a charge neutralization of the complex and the formation of a condensed structure.
These data show that the Lipid Polycation DNA gene delivery system may enable the systemic delivery of therapeutic genes, an important step in the evolution of gene delivery technologies.
Smooth muscle calponin and a 25-amino-acid actin-binding peptide (aa 151-175) derived from the myristoylated, alanine-rich, C kinase substrate (MARCKS) are two examples among polycations that appear to induce actin-bundle formation mainly by an electrostatic mechanism (Tang and Janmey, 1996; Tang et al.
The interaction depends on the conformation of the dye and the polycations as well.
The capillary is rinsed with buffer containing a polycation, which binds to the negatively charged silica surface of the capillary; this approach can diminish or even reverse the electroosmotic flow, depending on the nature of the polycation and its concentration.
Polyamines (PAs), namely putrescine (Put), spermidine (Spd) and spermine (Spm), are low molecular weight, aliphatic polycations found in the cells of all living organisms (Kusano et al, 2008).
The scientists created novel polycations, a polymer chain with positive charges, which is not too unusual.
CRP has the highest affinity to phosphocholine residues, but it can also bind to phosphoethanolamine, chromatin, histones, fibronectin, laminin and polycations (9).
Interaction of human erythrocyte multicatalytic proteinase with polycations.
Electric field directed growth and branching of cultured frog nerves, effects of aminoglycosides and polycations.