polycystic ovary syndrome

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polycystic ovary syndrome

a hormonal disorder in which the Graafian follicles in the ovary fail to develop completely so that they are unable to ovulate, remaining as multiple cysts that distend the ovary. The result is infertility, obesity, and hirsutism
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Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease.
The risk factors include cardiovascular disease, a family history of diabetes, overweight, a sedentary lifestyle, impaired glucose tolerance or impaired fasting glucose, hypertension, high triglyceride levels or low high-density lipoprotein cholesterol levels, and, in women, a history of gestational diabetes, birth of a baby weighing 9 pounds, or polycystic ovarian disease.
The study, conducted at a single center, utilized a double blind placebo controlled design to evaluate the effects of a single oral dose administered up to 6 weeks to 30 obese female subjects with polycystic ovarian disease.

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