In addition, phenotypes can arise from complex polygenic traits
, where an SNP only relates to one factor in the final phenotype.
Quantitative trait loci (QTL) analyses have been performed for economically important quantitative traits in beef cattle, since such genomic technologies can provide genetic dissection of polygenic traits
and help to understand the molecular mechanisms of the identified genes or genetic loci (Womack, 2006).
Genetic control of some polygenic traits
in vulgar species.
If we can understand the genetics of height, it will help us understand how other polygenic traits
are inherited," says Hirschhorn.
It describes the foundational genetics and statistical theory for established and new methodologies, focusing on polygenic traits
, through 22 chapters written by an international group of researchers in genetics, psychiatry, and psychology.
Taken together, these studies support the hypothesis that the formulation of dense genetic maps on the basis of single-nucleotide polymorphisms is an important approach to elucidating polygenic traits
of drug response and, in combination with appropriate nongenetic factors, might help to define a warfarin dose-response phenotype.
In what follows, whenever I refer to polygenic traits
or diseases, I assume, along with mainstream biology, strong environmental interaction.
Modeling of Polygenic Traits
to Improve the Predictiveness of Mouse Model Studies
However, the genetic improvement of polygenic traits
, like growth and meat production, can be enhanced by marker assisted selection which has higher accuracy in estimating the genetic value of animals (Dekker, 2004).
Our results suggest that the expanded MDR method better identifies interaction effects between multiple genes that are related to polygenic traits
, and that the method is an alternative to the current model choices to find associations of multiple functional SNPs and/or their interaction effects with economic traits in livestock populations.
c) A polygenic trait
may have several different phenotypes and genotypes.