polymyxin

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Related to Polymyxin B: bacitracin

polymyxin

[‚päl·i′mik·sən]
(microbiology)
Any of the basic polypeptide antibiotics produced by certain strains of Bacillus polymyxa.
References in periodicals archive ?
For stock solutions of polymyxins, colistin sulfate and polymyxin B powders (Sigma Aldrich) were diluted into MHB-CA medium in glass tubes to obtain a concentration of 0.
Detection of synergy using the combination of polymyxin B with either meropenem or rifampin against carbapenemase-producing Klebsiella pneumoniae.
Polymyxin B sulfate is an antibacterial drug used in the treatment of infections of the urinary tract, meninges and bloodstream caused by susceptible strains of Pseudomonas aeruginosa.
Researchers and physicians alike have been focusing on using combinations of colistin, polymyxin B, rifampin, and imipenem, although other drug combinations have been considered as well.
The sanctioned ANDA is bio-equivalent and therapeutically equal to the reference listed drug product (RLD) Polymyxin B for Injection USP, 500,000 units/vial of Eurohealth International Sarl.
cholerae O1 was found to be sensitive to polymyxin B (6).
11 January 2012 - Bedford Laboratories updated on Tuesday its guidance on its voluntary recall of Polymyxin B and Vecuronium Bromide, both for injections, in the US.
Pharmaceutical company Sagent Pharmaceuticals Inc (Nasdaq:SGNT) reported on Thursday the receipt of approval from the US FDA approval for polymyxin B for injection, USP in 500,000 units per vial, latex-free glass vials as an antibacterial drug.
Preliminary experience suggests that both the efficacy and safety of polymyxin B are reasonably good in the contemporary setting of multidrug-resistant Gram-negative infections, and the drug is worth considering in affected patients who are running out of commercially available antimicrobial options, according to two reports that were presented at the annual Interscience Conference on Antimicrobial Agents and Chemotherapy.
Time-kill studies (TKS) with polymyxin B at 1x MIC for strain 01, and 1/4, 1/2 and 1x MIC for strain 02 were performed in combination with fixed concentrations of imipenem (4 mg/L), meropenem (4 mg/L), rifampicin (1 mg/L), tigecycline (1 mg/L), amikacin (16 mg/L) and ceftazidime (mg/L).