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polymyxin |
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polymyxin [‚päl·i′mik·sən] (microbiology) Any of the basic polypeptide antibiotics produced by certain strains ofBacillus polymyxa. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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These multidrug-resistant (MDR) strains are sometimes susceptible only to polymyxins (colistin and polymyxin B), a class of antimicrobial drugs that has not been in widespread use for several decades and is more toxic than most currently used antimicrobial drugs. are frequent nosocomial pathogens and are commonly multidrug resistant, which leads to the extensive use of carbapenems and, lately, polymyxins. Thus, more toxic agents such as polymyxins have been used as alternative therapeutic drugs against multidrug-resistant Acinetobacter infections (5,6). |
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