(redirected from Polypeptides)
Also found in: Dictionary, Thesaurus, Medical.


see peptidepeptide,
organic compound composed of amino acids linked together chemically by peptide bonds. The peptide bond always involves a single covalent link between the α-carboxyl (oxygen-bearing carbon) of one amino acid and the amino nitrogen of a second amino acid.
..... Click the link for more information.



an organic compound containing six to 80–90 amino acid residues; the upper limit corresponds to a molecular weight of about 10,000. Such polypeptides, unlike proteins, can pass through semipermeable membranes.

The simple polypeptides are crystalline substances that are readily soluble in water and have chemical properties similar to those of amino acids. The complex polypeptides are amorphous and react with water to yield colloidal solutions. Polypeptides are formed in the organism during enzymatic proteolysis (autolysis of tissue, digestion, and so on) and during biosynthesis from amino acids. Many natural polypeptides exhibit the biological activity of hormones, antibiotics, and toxins. Synthetic polypeptides serve as models in studying the structure and biological activity of proteins.


A chain of amino acids linked together by peptide bonds but with a lower molecular weight than a protein; obtained by synthesis, or by partial hydrolysis of protein.
References in periodicals archive ?
Rob Hutchison, CEO said the company's team worked with Transcend in pre-clinical models to prove its utility to delivery therapeutic agents across the BBB as well as conducted over four years of experiments to find active polypeptide fragments from within the 738 amino acid sequence of Transcend that were involved in binding specific receptors that are involved in transport through the BBB.
The expression of only one polypeptide of 18 KDa remained same; however, fourteen polypeptides of 135, 132, 120, 110, 104, 62.
The properties of different protein products of genes are determined by the sequence of amino acids of the polypeptide chain and by the way in which the chain is folded.
We classified maize germplasm into various groups based on variation in zein polypeptides (Fig.
Difference observed was in molecular weights of two large proteins and remaining polypeptides exhibited similar protein patterns.
In the HGS case, the judges were asked to decide whether the predictions made by HGS on the function of the claimed polypeptide on the basis of gene sequence similarities were enough to satisfy the above rules.
coli), which has been genetically altered to produce a specific artificial polypeptide known as a chimeric polypeptide.
When we say we eat "complete proteins", what we are eating is food that contains all the EAA polypeptides which have formed into their fairly simple protein molecules.
com/research/nps3nn/research_report_on) has announced the addition of the "Research Report on Chinese Chemosynthetic Polypeptide Drug Industry, 2012" report to their offering.
MG isolates (n=12) were used for proteomics analysis and determination of immunogenic polypeptides.
During various physiological processes such as protein synthesis, degradation and transport through membranes, they bind to interactive sites of polypeptides thereby preventing their improper interaction with other molecules and enabling controlled further processing of the polypeptide in question.
Johnston, IA) has patented methods and compositions directed to the production of polypeptides in plant protein storage tissue.