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porphyria |
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porphyria [pȯr′fir·ē·ə] (medicine) A usually hereditary, pathologic disorder of porphyrin metabolism characterized by porphyrinuria and photosensitivity. Porphyria comes in a winter storm to show her devotion, and her lover strangles her with her own tresses. [Br. Poetry: Browning Porphyria’s Lover in Magill IV, 247] See : Love, Unrequited How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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That HCB can produce reproductive toxicity in humans was established in studies of women in Turkey, where consumption of bread made from grain treated with HCB from 1955 through 1959 resulted in widespread poisoning, primarily manifested as porphyria cutanea tarda, in which damage to the liver results in disruption of heme synthesis and accumulation of porphyrins (Peters et al. 26 Cell that a protein called PGC-l-alpha is the linchpin connecting fasting, glucose, and insulin with porphyria episodes. 2) Conditions affecting systems outside the liver include cutaneous manifestations (sporadic porphyria cutanea tarda and lichen planus), ocular lesions (Mooren's ulcers), sialadenitis, and B-cell lymphoma. |
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