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posttranslational modification
(redirected from Post-translational modification)

   Also found in: Wikipedia 0.03 sec.
posttranslational modification [‚pōs·tranz¦lā·shən·əl ‚mäd·ə·fə′kā·shən]
(cell and molecular biology)
Any polypeptide alteration that occurs after synthesis of the chain.


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Protocol chapters (29 in all) detail key steps in 2DE experiments, including sample preparation, staining, post-translational modification, spot identification, and bioinformatics.
Lee, (2008) Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase.
An added complexity is that post-translational modifications such as glycosylation are not genetically encoded and are therefore not identically reproduced.
 
 
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