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posttranslational modification |
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posttranslational modification [‚pōs·tranz¦lā·shən·əl ‚mäd·ə·fə′kā·shən] (cell and molecular biology) Any polypeptide alteration that occurs after synthesis of the chain. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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A particularly challenging area of study within proteomics is post-translational modification of proteins. having introduced ETD (electron transfer dissociation) in 2005 as the first vendor, Bruker Daltonics is now taking the next major step forward: data-dependent, intelligent combinations of CID and ETD on an HCT Ultra(TM) high-capacity ion trap for maximum information on sequence coverage and post-translational modifications in complex samples will be described. A chapter covering post-translational modifications describes detection of phosphorylated and glycosylated proteins as well as immunoaffinity chromatography, phosphopeptide mapping, and isotopic labeling and collision-induced dissociation strategies. |
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