Side effects such as acne and hirsutism occurred significantly more often among patients taking the prasterone
Endogenous: androstenediol, androstenedione, dihydrotestosterone, prasterone
, which is the hormone dehydroepiandrosterone (DHEA), was safe and effective for improving systemic lupus erythematosus (SLE) symptoms and cutting the need for steroids in a phase III trial of 346 women with mild to moderate disease, Dr.
The ovules contained Prasterone
in a lipophilic base manufactured by Recipharm of Sweden.
Prestara is a pharmaceutical formulation for oral administration that contains highly purified prasterone
, the synthetic equivalent of dehydroepiandrosterone, or DHEA, a naturally occurring hormone and the most abundant adrenal hormone in humans, as the active ingredient.
Genelabs formulation of Prestara is a highly purified synthetic form of DHEA, or prasterone
, and the patent covers the specific polymorphic formulation of DHEA used in Genelabs' most recent clinical trials.
which did not demonstrate a statistically significant benefit among the patients receiving prasterone
compared to the patients taking placebo.
The Genovate trial of prasterone
is being conducted in Taiwan, and is similar in design to our recently completed U.