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nonsense mutation
(redirected from Premature stop codon)

   Also found in: Medical, Wikipedia 0.02 sec.
nonsense mutation [′nän‚səns myü‚tā·shən]
(cell and molecular biology)
A mutation that changes a codon that codes for one amino acid into a codon that does not specify any amino acid (a nonsense codon).


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In test-tube studies, they demonstrated that human cells with a CFTR gene containing a premature stop codon could occasionally construct the full protein if treated with aminoglycosides.
 
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