Prodromal Period


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Prodromal Period

 

the period during which premonitory symptoms of a disease or condition appear. In the prodromal period of infections, the symptoms may be nonspecific, such as weakness, headache, and mild fever, or specific, for example, the spots on the buccal mucosa in measles (the Bel’skii-Filatov-Koplik symptom, or Koplik’s spots); laboratory test results reveal changes in the body. The prodromal period is preceded by the incubation period, during which there are no symptoms despite the infection. It is followed by a period of a developed clinical picture of the disease.

The prodromal period may also be observed in some noninfectious diseases. Thus, in the period preceding myocardial infarction, an increase in the frequency and severity of attacks of angina pectoris is observed, and changes in the cellular composition of the bone marrow are observed before the onset of leukemia.

References in periodicals archive ?
With regard to specific symptoms in the prodromal period, men were more likely than women to report weakness or clumsiness (50% men versus 37% women, p = .
If there is a prodromal period of insomnia before depressive symptoms emerge, more ecologically valid measures are needed to assess this relationship.
As the prodromal period at this point can only truly be identified in retrospect, we need to be cautious in identifying candidates for early intervention.
To reconstruct, rather than explain, the prodromal period leading up to the first episode of depression in a group of adolescents with first episode depression.
4) Our patient likewise did not have a history of an injection, but did have a short prodromal period of symptoms.
Here's how it works: A patient experiencing sudden circulatory arrest due to ventricular fibrillation or other causes typically has a 20- to 30-second prodromal period prior to loss of consciousness.
Here's how it works: A patient experiencing sudden circulatory arrest due to ventricular fibrillation or other causes typically has a 20-to 30-second prodromal period prior to loss of consciousness.
It is important to note that in this model, serum viral titers peak at day four after infection, indicating that BCX4430 has the potential to be an effective therapeutic when administered as pre-exposure prophylaxis; as post-exposure prophylaxis during the virus incubation period; and as a treatment during the prodromal period and symptomatic disease.
The constant inner tension during the election period could easily explain the initial PRODROMAL period, while the voting day on April 10, 2014 proved to be the trigger point for the onset of primary delusion.
Identifying patients in the early prodromal period offers the opportunity to more effectively engage them and form a therapeutic alliance.