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promoter
(redirected from Promoter region)

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia 0.03 sec.
promoter
1. Chem a substance added in small amounts to a catalyst to increase its activity
2. Genetics a sequence of nucleotides, associated with a structural gene, that must bind with messenger RNA polymerase before transcription can proceed

promoter [prə′mōd·ər]
(chemistry)
A chemical which itself is a feeble catalyst, but greatly increases the activity of a given catalyst.
(genetics)
The site on deoxyribonucleic acid to which ribonucleic acid polymerase binds preparatory to initiating transcription of a gene or an operon.


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? Mentioned in ? References in periodicals archive
 
MGMT normally plays a role in DNA repair, but when the promoter region near the MGMT gene acquires a group of methyl molecules, the gene switches off and MGMT production stops.
In the promoter region, adjacent to a binding site for the transcription factor Sp1 (Deakin et al.
The uses for this promoter region extend beyond controlled gene expression in skin cells.
 
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