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proteasome |
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proteasome [′prōd·ē·ə‚sōm] (biochemistry) A large proteolytic particle found in the cytoplasm and nucleus of all eukaryotic cells that is the site for degradation of most intracellular proteins. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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1997 "p53-dependent induction of apoptosis by proteasomes inhibitors". The aryl hydrocarbon receptor mediated degradation of estrogen receptor [alpha] through activation of proteasomes. A cell marks proteins with this "kiss of death" molecule--itself a small protein--and then shuttles the doomed proteins to its waste-disposal units, called proteasomes. |
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