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proteasome
(redirected from Proteasomes)

   Also found in: Wikipedia 0.01 sec.
proteasome [′prōd·ē·ə‚sōm]
(biochemistry)
A large proteolytic particle found in the cytoplasm and nucleus of all eukaryotic cells that is the site for degradation of most intracellular proteins.


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The blocking of the TB proteasome also appeared to be permanent, and was about a thousand times more potent than against human proteasomes, which were largely unaffected, Li said in a statement.
In this scenario, it can be anticipated that a crucial role is played by age-related structural and functional alterations and modifications of proteasomes and immunoproteasomes, the last being a key component of antigen processing and MHC class I antigen presentation.
In a researcher article in the journal Molecular Cell, the researchers describe proteasomes as "protein-digesting machines" that regulate cellular levels of various proteins, including that of the lethal BaxEi, by breaking them into smaller components within the cell.
 
 
 
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