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proteasome
(redirected from Proteasomes)

   Also found in: Wikipedia 0.01 sec.
proteasome [′prōd·ē·ə‚sōm]
(biochemistry)
A large proteolytic particle found in the cytoplasm and nucleus of all eukaryotic cells that is the site for degradation of most intracellular proteins.


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The aryl hydrocarbon receptor mediated degradation of estrogen receptor [alpha] through activation of proteasomes.
A cell marks proteins with this "kiss of death" molecule--itself a small protein--and then shuttles the doomed proteins to its waste-disposal units, called proteasomes.
 
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