Proteolysis (redirected from Protein degradation)

proteolysis

Process in which a protein is broken down partially, into peptides, or completely, into amino acids, by proteolytic enzymes, present in bacteria and in plants but most abundant in animals. Proteins in food are attacked in the stomach by pepsin and in the small intestine mainly by trypsin and chymotrypsin from the pancreas. Proteolytic enzymes are secreted as zymogens, which are themselves converted by proteolysis to their active forms. Many other zymogens or precursors undergo proteolysis to form active enzymes or proteins (e.g., fibrinogen to fibrin). In cells, proteolytic degradation of old proteins is part of cellular maintenance.

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proteolysis [‚prōd·ē′äl·ə·səs]

(biochemistry)

Fragmentation of a protein molecule by addition of water to the peptide bonds.

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Proteolysis 

the hydrolysis of peptide bonds that is catalyzed by proteolytic enzymes. During proteolysis, intrinsic proteins that are undergoing the catabolic process, as well as food proteins, are split into amino acids. Proteolysis is important in the formation of enzymes, hormones, and biologically active peptides from their inactive precursors. In plants proteolysis takes part in the mobilization of the storage proteins of seeds during germination.