protein kinase

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Related to Protein kinases: Phosphatases

protein kinase

[¦prō‚tēn ′kī‚nās]
(biochemistry)
An enzyme that exerts regulatory effects on growth and malignant transformation by phosphorylating proteins.
References in periodicals archive ?
Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload.
Isolation of a wheat cDNA clone for an abscisic acid-inducible transcript with homology to protein kinases.
Worley's team received another clue when they found that protein kinases also bind to Preso1.
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta.
In this study we established cooperative interaction between substrate binding sites of the cAMP-dependent protein kinase catalytic subunit (protein kinase A, EC 2.
Under the agreement, CRELUX and ProQinase will establish and continuously expand an off-the-shelf crystal-grade protein kinase portfolio, optimized and quality-controlled for successful crystallization.
Involvement of p44/42 mitogen-activated protein kinases in regulating angiotensin II-and endothelin-1-induced contraction of rat thoracic aorta.
He added that "Kinexus is routinely tracking over 1000 phosphorylation sites with its proteomics screening services, and it has already identified the JNK and p38 MAPK protein kinases as drug targets using the Kinetworks(TM) method.
The design of the active-site directed inhibitors of protein kinases has proceeded from structures of both of these substrates.
To explore further how interactions between the virus and these receptors might elicit cellular changes that contribute to HIV pathogenesis, his laboratory proceeded to run a series of experiments looking at protein kinases, enzymes important in relaying cellular signals.
8 Science, the scientists now identify it as dg2, a gene encoding three similar enzymes belonging to the class known as protein kinases.

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