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proteoglycan |
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proteoglycan [‚prōd·ē·ō′glī·kən] (biochemistry) A high-molecular-weight polyanionic substance covalently linked by numerous heteropolysaccharide side chains to a polypeptide chain backbone. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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2), the proteoglycans of the nucleus absorb so much water that the prolapsed material may now expand to 3 times its original enclosed size. The extracellular matrix (ECM) is composed of a great variety of molecules and includes collagen family, elastic fibers, glycosoaminoglycans and proteoglycans, and adhesive glycoproteins. The partial inhibition of SARS-CoV HSR1 by heparin suggests that the envelope proteins coating the SARS-CoV virions might be endowed with positively charged amino acids that could interact with negatively charged sulfate groups present on heparan sulfate proteoglycans expressed on the surface of target cells. |
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