Co-expression of the protooncogene
FOS (cfos) and an embryonic interferon (ovine trophoblastin) by sheep conceptuses during implantation.
Cell motility is controlled by 5F2/ASF through alternative splicing of the Ron protooncogene
Expression of the neu protooncogene
in the mammary epithelium of transgenic mice induces metastatic disease.
The best characterized tumorigenic molecular changes in FTC are activating point mutations in genes of the protooncogene
family comprising HRAS  (v-Ha-ras Harvey rat sarcoma viral oncogene homolog), KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog), and NRAS [neuroblastoma RAS viral (v-ras) oncogene homolog] and in the PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) fusion oncogene rearrangement (3); however, RAS gene mutations (a) occur only in 10%-25% of FTC cases, (b) are also seen in papillary thyroid carcinoma, and (c) occur equally often in FA and FTC (3-5).
Slamon DJ, Godolphin W, Jones LA, et al: Studies of the HER-2/neu protooncogene
in human breast and ovarian cancer.
Mutation scanning of the RET protooncogene
using high-resolution melting analysis.
Alterations of the p53 tumor suppressor gene and its association with activation of the c-K-ras-2 protooncogene
in pre-malignant and malignant lesions of the human uterine endometrium.
Differential hypomethylation of the c-myc protooncogene
in bladder cancers at different stages and grades.
The noncontinuous probes with omission of 1-3 nt of the template sequence were designed to mask nontargeted sequence variants such as benign polymorphic sites in RET protooncogene
and the fibroblast growth factor receptor 3 gene (FGFR3)  (3).
The p53 protooncogene
can act as a suppressor of transformation.
Transcriptional activation of c-fos protooncogene
by 16[beta]-estradiol: mechanism of aryl-hydrocarbon receptor-mediated inhibition.
Structural analysis of alpha-enolase: mapping the functional domains involved in down-regulation of the c-myc protooncogene