proximal convoluted tubule


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Related to proximal convoluted tubule: loop of Henle, Distal convoluted tubule, Collecting duct

proximal convoluted tubule

[′präk·sə·məl ‚kän·və′lüd·əd ′tüb‚yül]
(anatomy)
The convoluted portion of the vertebrate nephron lying between Bowman's capsule and the loop of Henle; functions in the resorption of sugar, sodium and chloride ions, and water.
References in periodicals archive ?
Therefore, it is very important to guarantee adequate seric concentrations of vitamin D and the substrate for 1,25(OH)2D to all patients with CKD, which have an important loss of proximal convoluted tubule cells due to their loss of nephron.
In managing diabetes SGLT2 inhibitors act by a novel insulin-independent mechanism by blocking glucose reabsorption in the proximal convoluted tubules resulting in markedly increased glycosuria a mechanism not limited by the degree of insulin resistance or beta-cell dysfunction.
We developed a new algorithm to calculate the fractal dimension of convoluted objects, like the outline images of a serially sectioned proximal convoluted tubule.
Analysis of volume, area and perimeter of cell nuclei in distal and proximal convoluted tubules and also the collecting duct of the kidney in rat fetuses treated with sodium cyclamate showed that there is significant difference in the dimensions for the treated group compared to the controls.
Effect of alphatocopherol on diameter of proximal convoluted tubules of kidney in diabetic mice.
The present study showed scattered groups of proximal convoluted tubules with granular cytoplasm and with swollen granular cytoplasm in Larus argentatus (Figure 8).
This showed that toxic dose of acetaminophen was responsible for tubular damage especially in proximal convoluted tubules after 48 hours.
CP is a widely used antineoplastic agent, but associated with nephrotoxicity, and prone to result in long-term renal fibrosis after administration, the damages involve both glomeruli and tubules, while the major damage happens in proximal convoluted tubules.
Relatively weak cytoplasmic staining of PAX2 in the podocytes of glomeruli and epithelial cells of proximal convoluted tubules is also detected (Figure 4, b).
The kidney section showed severe degeneration and necrosis of lining epithelium of its proximal convoluted tubules, while spleen section showed severe congestion of red pulp and a variable degree of lymphocytes depletion from white pulp follicles.
Results and Conclusions: Main morphological changes were seen in proximal convoluted tubules and glomeruli (HandE PAS).

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