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proximal convoluted tubule
(redirected from Proximal tubule)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
proximal convoluted tubule [′präk·sə·məl ‚kän·və′lüd·əd ′tüb‚yül]
(anatomy)
The convoluted portion of the vertebrate nephron lying between Bowman's capsule and the loop of Henle; functions in the resorption of sugar, sodium and chloride ions, and water.


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1999; 2001; 2003a; 2003b; 2005; Zager and Kalhorn, 2000) studied kidney responses to several forms of injury such as renal failure, sepsis, endotoxemia, ischemia-reperfusion or oxidative stress, and they showed that proximal tubule cells undergo some adaptive changes for protection from subsequent hazards.
Renal elimination is passive through the glomeruli of the kidney, while there is active reabsorption of potassium, along with sodium and chloride, in the proximal tubule and ascending limb.
Specific topics include the isolation and primary culture of human proximal tubule cells, the laser capture micro-dissection of kidney tissue, immuno and lectin histochemistry for renal light microscopy, identifying apoptosis in kidney tissue sections, and mechanical stretch-induced signal transduction in cultured mesangial cells.
 
 
 
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