For instance, Aqp3b is expressed in the basolateral membrane of chloride cells, but it is located apically in the kidney tubule cells of European eel; Aqp8b is localized in the apical membrane of enterocytes but is basolateral in proximal tubule
cells of Atlantic salmon.
This functional disorder in the kidney of fish produced abundant lesion in the proximal tubule
(Athikesavan et al.
It has further been shown that the effect of Ang II to increase proximal tubular chloride and water reabsorption decreases by about 75 per cent following renal denervation and only a very small portion of the Ang II effect ([approximately equal to]25%) can be ascribed to a direct action on Ang II receptors located on proximal tubules
Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule
Metallothionein isoform 3 and proximal tubule
vectorial active transport.
ATPase activity from basolateral membrane of the proximal tubule
1999; 2001; 2003a; 2003b; 2005; Zager and Kalhorn, 2000) studied kidney responses to several forms of injury such as renal failure, sepsis, endotoxemia, ischemia-reperfusion or oxidative stress, and they showed that proximal tubule
cells undergo some adaptive changes for protection from subsequent hazards.
Specific topics include the isolation and primary culture of human proximal tubule
cells, the laser capture micro-dissection of kidney tissue, immuno and lectin histochemistry for renal light microscopy, identifying apoptosis in kidney tissue sections, and mechanical stretch-induced signal transduction in cultured mesangial cells.
The proximal tubule
consists of cylindrical to height cuboidal cells, frequently denominated prismatic cells, and with high brush border (Figures 1a-d).
More recently, two experimental studies in hamster models reported down regulation of the proximal tubule
type III Na+/ [H.
Compare and contrast the mechanisms for sodium, chloride and water transport in the proximal tubule
, the thick ascending limb and the collecting duct.
1992 "The kidney androgen-regulated protein promoter confers renal proximal tubule
cell-specific and highly androgen-responsive expression an the human angiotensinogen gene in transgenic mice," Journal of Biological Chemistry 272(44): 28142-28148.