affect

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Related to Pseudobulbar affect: Pseudobulbar palsy

affect

Psychol the emotion associated with an idea or set of ideas

Affect

 

an emotional state that is characterized by a turbulent and relatively short course (rage, anger, horror, and so forth). The manifestation of affect is linked with sharply expressed changes both in the autonomous motor sphere (inhibition or overexcitation and disorder in the coordination of movement) and in the sphere of vegetative reactions (change of pulse and breathing, spasms of the peripheral blood vessels, the appearance of so-called cold sweat, and so forth). Affect can disturb the normal course of the higher psychic processes of perception and thinking and can cause a decrease in consciousness or its loss. Under certain conditions, negative affect can be fixated in the memory in the form of so-called affective complexes. These traces of past affective states can become reactivated in the present under the influence of irritants associated with the situation that caused the affect. Another important peculiarity of affect is that with the repetition of a negative affect which is caused by the same factor or analogous factors, its manifestation can be reinforced (the phenomenon of “accumulation” of affect), sometimes creating the impression of pathological conduct. The presence of strong affective states in a person at the time when he commits an action is regarded by the law as a circumstance that decreases the degree of his responsibility for these actions.

A. N. LEONT’EV

affect

[′af‚ekt]
(psychology)
Conscious awareness of feelings; mood.
References in periodicals archive ?
The causes and treatment of pseudobulbar affect in ischemic stroke.
Persistent pseudobulbar affect secondary to acute disseminated encephalomyelitis.
Baseline demographic characteristics, stratified by responder and pseudobulbar affect (PBA) symptom status.
Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis.
According to the company, people with pseudobulbar affect (PBA) have sudden outbursts of involuntary crying or laughing, even though there may not be anything particularly sad or funny to trigger those emotions.
A real reason for patients with pseudobulbar affect to smile.
According to the company, the US Patent, entitled "Pharmaceutical Compositions Comprising Dextromethorphan and Quinidine for the Treatment of Neurological Disorders," claims methods for treating pseudobulbar affect or emotional lability using low-dose quinidine formulations of NUEDEXTA.
16) Involuntary emotional expression disorder (IEED)--or pathologic laughing or crying--is a form of pseudobulbar affect.
Food and Drug Administration (FDA) has acknowledged receipt of the Company's Complete Response to the October 2006 Approvable Letter for Zenvia[TM] (dextromethorphan/quinidine) in the treatment of pseudobulbar affect (PBA).
M2 EQUITYBITES-November 18, 2011-Avanir Pharmaceuticals Inc's MAA for NUEDEXTA for pseudobulbar affect accepted by EMA(C)2011 M2 COMMUNICATIONS http://www.
AVANIR's lead product candidate, Zenvia, has completed a confirmatory Phase III trial in the treatment of pseudobulbar affect (PBA) and has successfully completed a Phase III trial for diabetic peripheral neuropathic (DPN) pain.
Nuedexta is indicated for the treatment of pseudobulbar affect (PBA).