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eosinophilia |
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eosinophilia [‚e·ə‚sin·ə′fil·ē·ə] (medicine) A greater than average number of circulating eosinophils. Also known as acidophilia; oxyphilia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice. The HLA class II transgenic mouse was shown to be an excellent model for studying the genetic and molecular basis of allergic hyperresponsiveness because, like humans, this mouse strain develops pulmonary eosinophilia, lung tissue damage, and airway hyperreactivity upon exposure to allergens. This model exhibits many of the hallmarks of allergic asthma such as increased HDM-specific IgE, elevated HDM-specific lympho-proliferative responses in lung-associated lymph nodes, antigen-induced bronchospasm, airway hyperresponsiveness, and pulmonary eosinophilia (14). |
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