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pyruvate
(redirected from Pyruvate kinase)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
pyruvate [pī′rĂ¼‚vāt]
(biochemistry)
Salt of pyruvic acid, such as sodium pyruvate, NaOOCCOCH3.


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Soya bean trypsin inhibitor (STI), fatty acid free bovine serum albumin (BSA), pyruvate kinase (PK), leupeptin, ATP, ADP, PCr, ethylene glycol-bis(2-aminoethyl)-N,N,N'N'-tetraacetic acid (EGTA), ethylenediaminetetraacetic acid (EDTA), and 4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid (HEPES) were from Roche, N,N-bis(2-hydroxyethyl)2-aminoethanesulphonic acid (BES), Cr, and other reagent grade chemicals used were from Fluka or Sigma.
When the cancer cells were found to switch to the other form of pyruvate kinase in the laboratory by knocking out production of PKM2, their growth was curbed.
 
 
 
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