But how did the transfer RNA
manage to take up its positions to form the proper proteins?
In the beginning, the driving force behind RNAs
was the preservation of specific timber types--a Douglas-fir RNA
or a ponderosa-pine RNA
, for example.
The work of Kornberg's team culminated in 2001 with two publications, one showing inactive RNA
polymerase and the other capturing the machinery during the transcription process.
Of the seropositive children, only 11% had HCV RNA
detectable by RT-PCR.
Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA
A total of nine RNA
isolation protocols were tested.
SUMMARY FIGURE GLOBAL VALUE OF RNA
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If we stay within the infectious diseases (ID) context for the moment, there can also be benefits to choosing RNA
as our target material even in living, DNA-based organisms.
It seems likely, however, that simple RNA
molecules on the primordial Earth would have consisted of mixes of both right- and left-handed forms.
is easily and successfully isolated from most cells and tissues, intact RNA
extraction from the pancreas is difficult due to the high level of its ribonucleases (RNases).
What hi and her colleagues discovered is quite common, RNA
molecules contained misspellings at more than 20,000 different places in the genome, with about 10,000 different misspellings occurring in two or more of the people studied.
This article will review some of the newer concepts driving RNA
out of the role of "messenger only" and into a role as a diagnostic and therapeutic agent.