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RNA polymerase I |
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RNA polymerase I [¦är¦en¦ā pə¦lim·ə‚rās ′wən] (cell and molecular biology) An enzyme found in the nucleolus that copies ribosomal genes to produce ribosomal ribonucleic acid. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| John Donelson (University of Iowa, Iowa City, IA) reviewed antigenic variation in Trypanosoma bruce; and recent findings on the use of an extranucleolar body containing RNA polymerase I to regulate expression of VSG genes. They saw a docking site that might reveal the starting point of transcription, a spot where the RNA polymerase is correctly situated on a gene. Transcription of some genes but not others by RNA polymerase is the basis for development of a single cell, the fertilized egg, into a human with many cell types. |
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