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Ras protein |
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Ras protein [¦är¦ā′es ‚prō‚tēn] (cell and molecular biology) A GTPase that is part of a signaling cascade that controls cell growth; it turns itself off by hydrolyzing guanosine triphosphate (GTP) to guanosine diphosphate (GDP); however, if left in its active (GTP-bound) form, it can lead to uncontrollable cell growth, or cancer. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Effect of association with adenylyl cyclase-associated protein on the interaction of yeast adenylyl cyclase with Ras protein. Mutant Ras proteins appear in many cancers, which is why the inhibitors have stirred so much excitement (SN: 5/3/97, p. The frequent detection of mutant ras proteins in pancreatic and other cancers provides strong support for their role as potential drug targets. |
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