rate-determining step

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rate-determining step

[′rāt di¦tər·mən·iŋ ‚step]
(chemistry)
In a multistep chemical reaction, the step with the lowest velocity, which determines the rate of the overall reaction.
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References in periodicals archive ?
The metalcasting facility has processed 24 heats in one day on occasion, but rate-limiting steps begin to appear, and often other departments cannot keep up with this pace unless under near perfect conditions.
A procedure for measuring peptides in rumen fluid and evidence that peptide uptake can be a rate-limiting step in ruminal protein degradation.
5 if the rate-limiting step in the hydrogen transport mechanism is diffusion and that transport is unidirectional.
In fact, such moves may actually highlight a lab's hidden operational inefficiencies, as getting samples to the automated system becomes the critical link and the rate-limiting step.
Cardiac myosin activators accelerate the rate-limiting step of the myosin enzymatic cycle and shift the enzymatic cycle in favor of the force-producing state.
Also, as the CIO or an IT professional, don't ever be the rate-limiting step, rather, you should be embracing of innovation.
This may be best visualized as a rate-limiting step or bottleneck in the overall process.
However, the decline in "physicians choosing generalist careers may be the rate-limiting step in the nation's ability to staff CHCs and may lead to renewed shortages of safety-net and rural physicians generally," they wrote.
For all three contaminants, longitudinal and tangential penetration rates were similar, indicating that the rate-limiting step may be contaminant evaporation inside the wood tracheids or contaminant dissolution in water (diffusion being controlled by strong contaminant sorption in wood).
In the mammalian brain, choline transport, and not the activity of choline acetyltransferase, is the rate-limiting step in ACh biosynthesis and the locus of regulation of ACh levels (Klemm and Kuhar 1979; Simon et al.

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