renal failure

(redirected from Renal impairment)
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renal failure

[′rēn·əl ′fāl·yər]
(medicine)
Severe malfunction of the kidneys, producing uremia and the resulting constitutional symptoms.
References in periodicals archive ?
6%) having mild renal impairment were managed conservatively with rehydration and/or diuretics with mortality of 18.
Although there are no dosage recommendations based on renal function provided by the labeling, there has been concern about the use of some FGAs in patients with renal impairment.
Patients with lesser degrees of renal impairment showed decreasing recovery following solvent extraction, in proportion to the severity of the renal impairment.
The association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.
The potential benefits of treatment with dalfampridine "should be carefully considered against the risk of seizures" before prescribing the drug to patients with mild renal impairment (creatine clearance 51 mL/min to 80 mL/min).
Compared to patients without renal impairment, patients with advanced CKD will likely have lower insulin requirements (Rave, Heise, Pfutzner, Heinemann, & Sawicki, 2001).
Risk factors that predispose patients to obstructive renal failure include severe volume depletion, underlying renal impairment, bolus drug administration and metabolic derangements such as metabolic acidosis or alkalosis.
The new data add to the large body of clinical evidence demonstrating that linagliptin cannot only achieve significant and sustainable reductions in blood glucose, but that based on its unique pharmacokinetic profile, linagliptin may not require dose adjustment even in patients with type 2 diabetes with any degree of renal impairment.
Although renal impairment is very common in patients with type 2 diabetes, early stage renal dysfunction often goes undiagnosed.
It was noted at that time that the patient had been continued on metformin 850 mg three times per day despite his renal impairment.
1) However, 1 study reported an incidence as high as 42% in patients with advanced renal impairment (serum creatinine >2.