renal failure

(redirected from Renal impairment)
Also found in: Dictionary, Thesaurus, Medical.

renal failure

[′rēn·əl ′fāl·yər]
(medicine)
Severe malfunction of the kidneys, producing uremia and the resulting constitutional symptoms.
References in periodicals archive ?
RUBY-I is evaluating VIEKIRAX (ombitasvir/paritaprevir/ritonavir tablets) + EXVIERA (dasabuvir tablets) with or without ribavirin (RBV) in treatment-naE[macron]ve, non-cirrhotic, genotype 1 (GT1) chronic hepatitis C patients with severe renal impairment (stage 4 or 5), including those on hemodialysis.
It is imperative that one is aware of its clinical manifestations on acute ingestion and that it may potentially cause chronic renal impairment when recurrently applied to unprotected skin.
Additionally, the FDA-approved label includes a clinical study in people with severe chronic renal impairment.
The potential benefits of treatment with dalfampridine "should be carefully considered against the risk of seizures" before prescribing the drug to patients with mild renal impairment (creatine clearance 51 mL/min to 80 mL/min).
In addition, samples from 107 patients with different stages of renal impairment were obtained and irreversibly anonymized as per Royal College of Pathology, UK, guidelines (D035, September 2007).
The half-life of sugammadex in patients with mild renal impairment is four hours (2).
Compared to patients without renal impairment, patients with advanced CKD will likely have lower insulin requirements (Rave, Heise, Pfutzner, Heinemann, & Sawicki, 2001).
Patients present with a pentad of fever, haemolytic anaemia, thrombocytopenia, renal impairment and neurological dysfunction.
The data suggest that linagliptin would not need dose adjustment in patients with type 2 diabetes regardless of the stage of renal impairment.
A total of 21 women (21%) had renal impairment, with a mean serum creatinine of 144 [micro]mol/L.
1) However, 1 study reported an incidence as high as 42% in patients with advanced renal impairment (serum creatinine >2.