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Repressor
(redirected from Repressor Protein)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
repressor: see nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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repressor [ri′pres·ər]
(biochemistry)
An end product of metabolism which represses the synthesis of enzymes in the metabolic pathway.
(genetics)
The product of a regulator gene that acts to repress the transcription of another gene.
Repressor 

a special regulating protein formed in bacterial cells that halts transcription, which is the synthesis of messenger ribonucleic acid (m-RNA) from a specific operon (a group of genes that carry out the synthesis of functionally related enzymes). The number of different repressors corresponds to the number of operons.

Unlike other proteins, a repressor present in a cell consists of ten to 20 molecules. The synthesis of m-RNA ceases when a repressor combines with an operator, which is the regulating part of an operon. An effector, for example, lactose in a lactose operon, interacts with a repressor to form a complex that inactivates and produces a reversible spatial change in a repressor molecule. This type of repressor can no longer combine with an operator and, as a result, m-RNA synthesis resumes.
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The second genetic construct comprises a second regulatory region in operative association with a nucleic acid molecule, or a derivative thereof, encoding a repressor protein, the repressor protein exhibiting both repressor operator sequence binding activity and repressor activity.
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For example, repressor proteins may bind to specific segments of DNA, preventing expression and thus the formation of the product of that DNA segment.
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Proteins called repressor proteins keep the OPCs in an immature state.
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