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Repressor
(redirected from Repressor Protein)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
repressor: see nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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repressor [ri′presĀ·ər]
(biochemistry)
An end product of metabolism which represses the synthesis of enzymes in the metabolic pathway.
(genetics)
The product of a regulator gene that acts to repress the transcription of another gene.

Repressor 

a special regulating protein formed in bacterial cells that halts transcription, which is the synthesis of messenger ribonucleic acid (m-RNA) from a specific operon (a group of genes that carry out the synthesis of functionally related enzymes). The number of different repressors corresponds to the number of operons.

Unlike other proteins, a repressor present in a cell consists of ten to 20 molecules. The synthesis of m-RNA ceases when a repressor combines with an operator, which is the regulating part of an operon. An effector, for example, lactose in a lactose operon, interacts with a repressor to form a complex that inactivates and produces a reversible spatial change in a repressor molecule. This type of repressor can no longer combine with an operator and, as a result, m-RNA synthesis resumes.



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The second genetic construct comprises a second regulatory region in operative association with a nucleic acid molecule, or a derivative thereof, encoding a repressor protein, the repressor protein exhibiting both repressor operator sequence binding activity and repressor activity.
For example, repressor proteins may bind to specific segments of DNA, preventing expression and thus the formation of the product of that DNA segment.
Proteins called repressor proteins keep the OPCs in an immature state.
 
 
 
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