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retinoid receptor |
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retinoid receptor [′ret·ən‚ȯid ri‚sep·tər] (cell and molecular biology) Any member of a family of nuclear receptors that mediate the actions of natural and synthetic analogs of vitamin A (retinoids) by regulating the transcription of retinoid-responsive genes in the cell nucleus. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Meanwhile, 9-cis-retinoic acid (9-cis-RA) can bind another series of retinoid receptors, termed retinoid X receptors (RXR), and initiate transcription of RXR responsive genes in a ligand-dependent fashion (discussed by Rohde et al. Researchers have identified several distinct retinoid receptors on cell nuclei membranes that appear related to other receptors known to regulate genes in this way. The Allergan retinoid receptor research team that discovered TAZORAC(R) ( |
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