retrosynthetic analysis

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retrosynthetic analysis

[‚re·trō·sin¦thed·ik ə′nal·ə·səs]
(organic chemistry)
A method for planning an organic chemical synthesis in which the desired product molecule is considered first, and then steps are considered one at a time leading back to the appropriate starting materials.
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At that point, a very large part of routine organic chemistry is going to get a lot more routine, and coming up with a good old-fashioned retrosynthesis is going to become a lot less of an intellectual exercise.
Later chapters treat interconversion of functional groups, protecting groups, enantioselective synthesis, and retrosynthesis.
Since the first edition of this book, which was the first to provide a structured course in retrosynthesis, Dr.