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Rous sarcoma |
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Rous sarcoma [′rau̇s sär′kō·mə] (veterinary medicine) A fibrosarcoma that can be produced in chickens, pheasants, and ducklings inoculated with the filterable, ribonucleic acid Rous virus. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The first tumor-causing virus identified in any organism was the Rous sarcoma virus in chickens. As a graduate student at the time, I observed that CEF of COFAL-positive embryos complemented envelope-defective Rous sarcoma virus, yielding pseudotype viruses with xenotropic properties. They then isolated any strands that bound to Rous sarcoma virus, an avian virus of the same family as HIV, the AIDS virus. |
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