Rosen presents extensive details of the day-day work done by Raul Ehrlich and his collaborators as they pursued his "magic bullet" theory of disease and discovered the antibiotic Salvarsan
pluma fuente que asesinaba al lapiz y al manguillo, Salvarsan
One of the early chemicals developed by Ehrlich which was both remarkably nontoxic to humans and remarkably toxic against a number of treponemal diseases (including syphilis and yaws) was the arsenical compound, Salvarsan
arsphenamine, which was also called the "magic bullet".
Over four centuries later, in 1909, Paul Ehrlich introduced the compound arsphenamine, more commonly referred to as Salvarsan
, as an alternative therapy to replace mercury treatment.
Conceptos quimicos, tecnologicos e histologicos de los colorantes de anilina>> (4), asi como su trabajo sobre colorantes quimicos en la Clinica Medica de Berlin, en calidad de asistente del profesor Frerichs (2), lo conducirian mas adelante a descubrir el salvarsan
, primer medicamento curativo conocido contra la sifilis.
Finally, and most alarmingly, Everybody's Family Doctor advises people with warts to drink poison: Internally, arsenic in small doses, Epsom salts, or green iodine of mercury will sometimes produce a cure; and the injection of salvarsan
(an arsenic preparation) is successful in some cases.
A simple apparatus for the intravenous (or intramuscular) injection of salvarsan
La reaccion Wasserman da resultados negativos, pero la cantidad de leucocitos en sangre motiva un tratamiento con salvarsan
Asi actuo durante mucho tiempo Paul Erhlich antes de curar la sifilis con el salvarsan
o Fleming con la penicilina.
But the discovery that a committee of Soviet doctors prescribed the medicine Salvarsan
, an arsenic-based treatment that is used only to treat syphilis, was a strong indication that his doctors knew the true nature of his disease.
He subsequently achieved fame with the development of Salvarsan
, an early treatment for syphilis.
A case of pyrogens linked to the contamination of certain batches of intravenous drugs came to light a 100 or so years ago when the Nobel Prize-winning doctor Paul Ehrlich developed Salvarsan
, the first treatment for syphilis.