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DNA sequencing
(redirected from Sanger method)

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DNA sequencing [¦dē¦en¦ā ′sē·kwən·siŋ]
(cell and molecular biology)
The determination of the sequence of nucleotides in deoxyribonucleic acid (DNA) molecules.
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Having identified 23 candidate single letter changes in the DNA, they amplified the regions containing these candidates and checked the sequences using the standard Sanger method.
Scientists make first direct measurement of mutation rate in humans by Asian News International
Four major discoveries stand out like signposts in the short history of molecular-based, evolutionary biology: the identification of the structure of DNA; (1) isolation of restriction endonucleases; (9,10) development of the Sanger method of DNA sequencing; (11) and, finally, the invention of the polymerase chain reaction (PCR).
Zippers, scissors and xeroxes: from unravelling the double helix to ... by Downing, Trisha Lee / Traffic (Parkville)
The most widely used technology for DNA sequencing is a capillary electrophoresis-based (CE) system employing the Sanger method.
Next-generation DNA sequencing by Instrument Business Outlook
 
 
 
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