and alanine were quantified in plasma by gas-chromatograph mass spectrometry.
It is very easy to identify sarcosine
in urine, which is a less invasive test than the blood analysis needed for the standard prostate-specific antigen (PSA).
Tests for elevated sarcosine
also outperformed the most widely used clinical test for detecting prostate cancer.
HHMI investigator Arul Chinnaiyan and colleagues at the University of Michigan showed that as prostate cancer develops and progresses, sarcosine
levels increase in both tumour cells and urine samples, suggesting that measurements of the metabolite could aid in non-invasively diagnosing the disease.
5 per cent sodium lauryl sarcosine
(sarcosyl), lysozyme, 1 mg/ml).
N-acyl sarcosinates are excellent candidates for these environmentally-conscious cleaners as they are produced by the reaction of the amino acid sarcosine
with a fatty acid chloride.
5 M EDTA, 1% N-lauroyl sarcosine
, 1 mg/mL Proteinase K; pH 8.
05% sodium lauroyl sarcosine
with pH adjusted to 7.
Other prostate cancer-specific genes, includingPCA3 (prostate cancer antigen 3) (6),  TMPRSS2-ERG (transmembrane protease, serine 2) (7), DNA methylation (8), ERG (v-ets erythroblastosis virus E26 oncogene homolog) (9), annexin A3, and sarcosine
, some of which have been proposed in combination (10, 11), have raised enthusiasm throughout the scientific community.
We now manufacture the entire Hamposyl line of specialty anionic surfactants--the N-acyl sarcosines
and their salts, the sarcosinates--using the still-unique Schotten-Baumann technology to react the amino acid sarcosine
with a fatty acid chloride," he said.
the leader in metabolomics-driven biomarker discovery and analysis, today announced that it has released mFocus TST[TM] (Tissue-based Sarcosine
Test), a research use only assay that measures the level of sarcosine
in a biological sample.
Folate (5-methyltetrahydrofolate), riboflavin, flavin mononucleotide (FMN),  FAD, pyridoxal 5'-phosphate (PLP), pyridoxal (PL), pyridoxic acid, free choline, betaine, dimethylglycine, creatinine, methionine sulfoxide, arginine, asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), tryptophan, kynurenine, kynurenic acid, anthranilic acid, 3-hydroxykynurenine, xanthurenic acid, 3-hydroxyanthranilic acid, and formiminoglutamic acid, were determined by liquid chromatography--tandem mass spectrometry (14-17), and methylmalonic acid, total homocysteine, total cysteine, methionine, serine, glycine, cystathionine, and sarcosine
by gas chromatography-tandem mass spectrometry (15, 18).