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Sarcosine

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sarcosine [′sär·kə‚sēn]
(organic chemistry)
CH3NHCH2COOH Sweet-tasting, deliquescent crystals; soluble in water, slightly soluble in alcohol; decomposes at 210-215°C; used in toothpaste manufacture. Also known as methyl glycocol.

Sarcosine 

(also N-methylglycine), CH3NHCH2COOH, a methyl derivative of the amino acid glycine. It is an intermediate metabolic product, serving in the body as a source of methyl groups in transmethylation reactions. Sarcosine is a component of creatine in the muscles and of the group of antibiotics called actinomycins.



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One HHMI investigator and colleagues at the University of Michigan showed that as prostate cancer develops and progresses, sarcosine levels increase in both tumor cells and urine samples, suggesting that measurements of the metabolite could aid in non-invasively diagnosing the disease.
Arun Sreekumar, the study not only proves that sarcosine is a marker of cancer aggressiveness, but also that it is highly associated with tumour development as well.
A compound called sarcosine may distinguish slow-growing prostate cancers from those likely to spread and become lethal, a new study shows.
 
 
 
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