SeMet was the major compound identified in the gastrointestinal extract while SeMet selenoxide
was its main degradation product formed after medium and long-term sample storage, respectively.
It is only after four in situ chemical transformations (oxidation to the selenoxide
, [2,3]-sigmatropic rearrangement, a second oxidation and loss of allyl alcohol) that the true catalyst (4) is generated (equation 1).
Elimination and [2,3]-Sigmatropic Rearrangement
Stoffregen University of Photochemistry of aromatic Wisconsin-River sulfoxides and Falls selenoxides