Shwartzman phenomenon

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Related to Shwartzman reaction: atelectasis, Arthus reaction, Koch phenomenon, Gregory Shwartzman

Shwartzman phenomenon

[′shwȯrts·mənfə‚näm·ə‚nän]
(immunology)
A type of local tissue reactivity in the skin in which a preparatory injection of the endotoxin is followed by an intravenous injection of the same or another endotoxin 24 hours later, producing immediate neutropenia and thrombopenia with the development of leukocyte-platelet thrombi with subsequent hemorrhage.