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single nucleotide polymorphism |
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single nucleotide polymorphism [¦siŋ·gəl ¦nü·klē·ə‚tīd ‚päl·ē′mȯr·fiz·əm] (genetics) A single base-pair difference between two copies of a deoxyribonucleic acid sequence from two individuals. Abbreviated SNP. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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A common type of variation is a trade of one letter for another, known as a single-nucleotide polymorphism (SNP, pronounced "snip"). Traditional immunodiagnostic products are being replaced by techniques such as in situ hybridization (ISH), fluorescent in situ hybridization (FISH), single-nucleotide polymorphism (SNP) detection, and sequencing technologies that are much more capable of assessing the presence and prognosis of cancer's complex molecular profile. The technology "reverse purification" enables full automation, reduces sample-processing time and allows for minimum sample volumes as required by high throughput laboratories for use in applications such as whole genome analysis, single-nucleotide polymorphism discovery, drug discovery research, toxicology analysis and pharmacogenomics. |
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