Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,918,589,048 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

Southern blotting
(redirected from Southern blot)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
Southern blotting [′sə·th·ərn ‚bläd·iŋ]
(cell and molecular biology)
A technique for the detection of specific sequences among deoxyribonucleic acid (DNA) fragments whereby the fragments are separated by gel electrophoresis and then blotted onto a sheet of nitrocellulose for detection with radioactively labeled nucleic acid probes. It was first described by E. M. Southern in 1975.


Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Mentioned in?  References in periodicals archive?   Encyclopedia browser?   Full browser?
No references found
 
The diagnosis of B-cell lymphoid malignancy can frequently be substantiated by detecting clonal immunoglobulin heavy chain (IGH) gene rearrangements, which is typically done by polymerase chain reaction (PCR) amplification and/or Southern blot analysis.
Plasmid DNA was not detected in any of these preparations, either when analyzed by agarose gel electrophoresis or after Southern blot hybridization analysis with a [bla.
False negatives in this study were excluded by subsequent analysis with the Southern blot technique.
 
 
 
Encyclopedia
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.