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Spermatogonium
(redirected from Spermatogonial stem cell)

    Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
spermatogonium [spər‚mad·ə′gō·nē·əm]
(histology)
A primitive male germ cell, the last generation of which gives rise to spermatocytes.
Spermatogonium 

a developing male sexual cell during the period of division prior to growth. Spermatogonia are in a state of rapid mitotic division. Primary and secondary spermatogonia are distinguished in insects and certain other invertebrates; secondary spermatogonia, the smaller of the two types, are surrounded by cells that form the seminal vesicle, or spermatocyst. Mammals have two types of spermatogonia, which differ in degree of differentiation and in chromatinic structure. The duration of the period of division varies from one animal species to another, depending on the number of generations and the rate of division of spermatogonia—parameters that are constant for eachspecies. Spermatogonia are formed in the parietal layer of the seminiferous tubules. Many animals have a specific zone of division in the cecum of the testes.
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After further differentiation, these in vitro derived germline stem cells expressed markers which are specific to primordial germ cells, spermatogonial stem cells, meiotic (spermatocytes) and post meiotic germ cells (spermatids and sperm).
North research offers hope to infertile couples by The Journal (Newcastle, England)
A new technique "We developed a strategy for the establishment of spermatogonial stem cell lines from embryonic stem cells," Nayernia said on his website, but added that further research would be needed to see if they could develop.
Sperm made from stem cells put men on notice by Al Arabiya (Saudi Arabia)
If we know more about how spermatogonial stem cells turn into sperm cells, this knowledge could be translated into treatments for men whose sperm is dysfunctional, although this is several years down the line.
Breakthrough could solve male infertility by Evening Chronicle (Newcastle, England)
 
 
 
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