Sphex


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Sphex

 

a genus of wasps of the family Sphecidae. The body length is 12–30 mm. The adults feed on flowers while the larvae feed on long-horned grasshoppers, crickets, small locusts, and other insects that have been paralyzed by the sting of an adult female sphex. The female digs a hole in the ground and then begins her search for prey, which she paralyzes by inserting her stinger into the thoracic nerve ganglia. She places the prey in the hole and lays an egg on it. After filling the hole with food, the female seals it and begins digging a new one. The paralyzed insects remain alive for as long as 40 days.

There are about 250 widely distributed species of spheges; about 50 species occur in the USSR. The wasps have very little practical significance. The species S. aegyptiacus usually follows injurious migratory locusts and preys upon them.

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announced today that they have entered into a biopharmaceutical development and manufacturing agreement for process development and manufacture of cGMP batches of Enobia's recombinant enzyme sPHEX Metallo Peptidase.
sPHEX is an enzyme replacement therapy for the treatment of X-linked Hypophosphatemia (XLH), the most prevalent form of inherited rickets affecting around 40,000 people.
As sPHEX has shown promising preclinical results, our partnership with Laureate Pharma is a crucial step in our manufacturing strategy.